Serial oparty jest na prawdziwej historii pionierów badania ludzkiej seksualności – Virginii Johnson oraz Williama Mastersa. Razem pracują nad seksualną rewolucją, która daje im sławę.

Sezony

Sezon	Odcinki	Data premiery	Ranking
Sezon 1 In 1956, former nightclub singer and single mother Virginia Johnson becomes the assistant to renowned OBGYN William Masters. They embark on their pioneering study in human sexuality while trying to navigate their personal feelings for each other. Masters' wife Libby tries to conceive a child to s…	12	2013-09-29	7.4
Sezon 2 Dr. William Masters and Virginia Johnson struggle to get their work back on track while taking their relationship to a much more intimate place. Libby flounders in a loveless marriage and turns to volunteering. Former prostitute Betty DiMello tries for the American dream and ends up working with …	12	2014-07-13	7.2
Sezon 3 Welcome to the swinging sixties. Thrust into the spotlight by the publication of their controversial study, Dr. William Masters and Virginia Johnson find themselves the unlikely leaders of the sexual revolution. But as newfound fame and pressures mount, their relationship becomes twisted and tang…	12	2015-07-12	6.6
Sezon 4 The seventies are in full swing and sexual experimentation is all the rage. Masters and Johnson should be celebrating, but their clinic is in legal trouble, their personal lives are in tatters and their relationship is on the rocks.	10	2016-09-11	6.7